- Postdoctoral Training, University of Pennsylvania, 2016-2022
- Ph.D., Molecular Biology, Princeton University. Princeton, New Jersey, 2016
- B.S., Biology, The College of New Jersey. Ewing, New Jersey, 2010
Stem cells are required for tissue repair in response to damage or aging. Accomplishing repair often requires intimate association between stem cells and their niche, a cellular microenvironment that maintains stem cells and regulates their behavior. To ensure that niche signals are restricted to the stem cells, tissues establish a paradigmatic compartmentalization of niche cells during development. The Anllo lab is working to understand the regulation of cell signaling, gene expression, and cell biological responses required to compartmentalize the niche. The lab leverages the fruit fly male gonad as a model system. This system enables us to employ powerful Drosophila genetics and in vivo live imaging coupled to incisive optogenetic approaches. Our ultimate goal is to reveal the cellular dynamics and molecular mechanisms required to assemble a functional stem cell niche, contributing to the fields of stem cell biology and tissue formation.